Bring someone with you to your appointment if doing so will help you feel more comfortable. Letrozole is also prescribed off-label for certain types of infertility. Fatigue was felt by almost 10% of people taking letrozole for breast cancer. To help keep your bones healthy you can increase your intake of calcium and vitamin D. Most people do this by taking a supplement. Nicole E. Cieri-Hutcherson, PharmD, BCPS, NCMP. These include side effects such as flushing, hot flashes, or headaches. So, blocking the actions of aromatase lowers estrogen levels in postmenopausal women. To hear from us, please sign up below. Feels like a UTI, but when I have my PCP test my urine there is no UTI. You can unsubscribe at any time. All rights reserved. Many people feel low or depressed. letrozole is for use only in women who can no longer get pregnant. Avoid driving or hazardous activity until you know how letrozole will affect you. A burning feeling when you pee. Other side effects Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. They may be able to put letrozole tablets in an easy-open container. Use effective birth control if you are not past menopause. How to Reduce Your Risk of Breast Cancer: 10 Lifestyle Recommendations, Symptoms of Late Stage Metastatic Breast Cancer, What to Know and Consider Before Having Prophylactic Mastectomy. Letrozole is usually taken for 5 years, may be recommended for up to 10 years depending on your individual circumstances. Mild side effects of many drugs may go away within a few days or a couple of weeks. Letrozole is sometimes used off-label to treat infertility in females. Atypical manifestations, such as cholestasis, chronic hepatitis, precipitation of acute-on-chronic liver failure, and autoimmune hepatitis, are reported with EBV infection, whereas cholestasis, portal vein thrombosis, and Budd-Chiari syndrome are reported with CMV infection. Medically reviewed by Drugs.com. Dosage of drugs is not considered in the study. Make note of all your symptoms. Common side effects may include: redness, itching, or mild skin irritation where a patch was worn or the gel was applied; dizziness, drowsiness; dry mouth; dry eyes, blurred vision; or. By signing up, I agree to GoodRx's Terms and Privacy Policy, and to receive marketing messages from GoodRx. Your doctor or pharmacist can tell you about any interactions these items may cause with letrozole oral tablets. Do not drive or operate machinery until you know how the medication affects you. Talk with your doctor about your health history before you take letrozole oral tablets. You should always consult your doctor or another healthcare professional before taking any medication. If youre concerned about this you may find it helpful to speak to your specialist. visible water retention temporary redness of face and neck weight gain headache nausea generalized weakness drug-induced hot flashes INFREQUENT side effects If experienced, these tend to have a. This is when part of the blood clot breaks away and travels to the lung. More than 25% of people reported joint pain in letrozoles clinical trials. I . In studies, joint pain was a common side effect of letrozole. Although not all of these side effects may occur, if they do occur they may need medical attention. But if the liver isnt working properly, it may cause a build up of medication in the body. Their risk is higher because of the cancer itself and some treatments for breast cancer. They may be able to offer ways of improving your symptoms. What are some frequently asked questions about letrozole? Ditropan (oxybutynin)." 2. Brand name: Femara Learn more about some of the side effects letrozole oral tablets may cause. GoodRx provides no warranty for any information. 3. The most common side-effects of treatment are hot flushes, sweating, joint pain, and feeling tired. Some side effects may not be reported. If dizziness persists see your GP. I'm sure Letrozole/Femara is the cause of the joint pain. Ch nh: iu tr tnh trng c ch th lc hoc tm thn vi suy gim hot ng v trng thi suy nhc: How to store letrozole. For example, it may be possible to switch to another aromatase inhibitor to see if your pain improves, or some people might be offered the drugtamoxifenas an alternative. What should I know about letrozole vs. anastrozole? All rights reserved. You may also want to eat more foods that are rich in calcium, such as milk, cheese, yoghurt and cereals. O 0. You don't really "catch" the infection from someone. But it can impact some of side effects of the drug. You may also experience weight gain with letrozole if you have swelling, which is another possible side effect of the drug. But if they become bothersome, talk with your doctor or pharmacist. If its hard for you to read the label on your prescription, tell your doctor or pharmacist. Taking letrozole with or after food can help reduce nausea. Learn. When this happens before menopause, it causes a higher release of other hormones necessary for fertility. Using a wrist splint can help. Letrozole has some serious side effects. If you have diarrhoea, its important to drink enough fluids. These symptoms can include: An itchy or burning sensation in your vagina and vulva. , , (2022). Swelling from letrozole usually occurs in your arms, feet, hands, or legs. You may have specific questions about using letrozole for infertility, such as: Because this isnt an approved use for letrozole, the manufacturer of the drug doesnt provide dosage guidelines for infertility treatment. Whether youve been prescribed letrozole for breast cancer or infertility, you may be wondering about what side effects to expect. Examples of OTC medications include acetaminophen (Tylenol) and ibuprofen (Advil). Warnings You should not use letrozole if you are pregnant. Here are a few questions you may want to ask: To get information on different conditions and tips for improving your health, subscribe to any of Healthlines newsletters. Rabaglio, M., et al. Even if you transfer Candida onto another person, they likely won't develop a yeast infection unless they are already prone to the condition. Find out more aboutdiet and breast cancer treatment. For instance, your doctor may prescribe other breast cancer treatments, such as fulvestrant, in addition to letrozole. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Dizziness Letrozole may cause dizziness. It can also be a side effect of immunotherapy medications. Doing so may help lessen your discomfort. To learn more, visit their websites. More serious side effects are possible, including bone fractures and complications from high cholesterol. Generic name: letrozole [LET-roe-zol] Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. Tell your doctor if you think you may be pregnant. If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date. In clinical studies, people with liver disease had higher levels of letrozole in their body. Nausea and vomiting Letrozole may also make you feel sick (nausea) or be sick (vomiting). Its also important to keep active and eat a high-fibre diet to avoid constipation. This rapid growth of cells can cause a tumor to form in your breast. This enzyme changes androgen hormones (like testosterone) found in skin, muscle, and fat cells into estrogen. Letrozole is a hormone therapy for breast cancer. Stop using OXYTROL immediately and get emergency medical treatment right away if you have any of these symptoms. They work by decreasing the amount of the hormone estrogen in your body. Letrozole comes as tablets that youll take by mouth. They can suggest ways to help you manage a body weight thats healthy for you. This includes the side effect hypogonadism (a condition in which the body doesnt produce many, or any, sex hormones.). More serious letrozole side effects are also possible. You may feel like your heart is racing (heart palpitations) when taking letrozole, which is more common in older people. Metformin is a drug thats typically used to treat diabetes. But, you should always talk with your doctor before starting any new medications or supplements while receiving cancer treatment. Brisk walking can also be beneficial. What is hormone-receptor-positive breast cancer? 31 Aug 2021 13:51 in response to EllieJ. Your doctor will recommend the dosage of letrozole oral tablets thats right for you. Femara is often given to women who have been taking tamoxifen ( Nolvadex, Soltamox) for 5 years. (2021). So, dont be afraid to ask questions or offer feedback on your treatment. Both medications belong to a group of drugs called aromatase inhibitors. They can also suggest ways to help reduce side effects. Your GP or specialist can refer you for counselling or may suggest you take an antidepressant drug. If your cancer is hormone receptor-negative, then letrozole will not be of any benefit. Letrozole (Femara ) is an oral medication that your doctor has prescribed for the treatment of your hormone-receptor-positive breast cancer. Some people find counselling or mindfulness helpful. Holding the ice pack or heating pad on your head for about 10 minutes a few times a day when youre having a headache is recommended. Dont take more letrozole oral tablets than your doctor prescribes. You may find your side effects reduce after stopping letrozole, for others they may continue after treatment finishes. Before taking letrozole oral tablets, be sure to tell your doctor about all medications you take, including prescription and over-the-counter types. When will I ovulate after taking letrozole. (2009). These drugs include: This list doesnt contain all types of drugs that may interact with letrozole oral tablets. Pharmaceutical Society of Australia "APPGuide online. Alcohol isnt known to interact with letrozole. Have your blood work and bone density checked as you have been told by your doctor. You may have menopausal symptoms such as hot flushes, sweating, sleep disturbance, vaginal irritation such as dryness and itching, and reduced libido (sex drive). Try to avoid alcohol, caffeine, or smoking, because they can worsen these symptoms. But your doctor will recommend if its something you should do. Registered Office: Fifth Floor, Ibex House, 42-47 Minories, London EC3N 1DY. They can assess you and offer advice on how to manage your energy levels. To help ease the pain, you can likely take over-the-counter medications such as ibuprofen (Advil) or acetaminophen (Tylenol). People with a DVT are at risk of developing a pulmonary embolism (PE). When estrogen isnt being made, your body can ovulate. But its also sometimes prescribed to help treat other PCOS-related conditions, such as elevated blood sugar levels and insulin resistance. Urinary tract infection is found to be associated with 4,007 drugs and 3,704 conditions by eHealthMe. New England Journal of Medicine. Its important to keep up with regular screenings for bone loss and cholesterol changes while taking letrozole. Its important to discuss all your concerns with your doctor. Yeast infections are caused by an overgrowth of a certain type of fungus, resulting. Here, well dive deeper into some common letrozole side effects you should know about. But it can still happen. Dosage form: oral tablet (2.5 mg) Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed. Talk with your doctor or pharmacist if you have questions about taking supplements or other ways to prevent or manage weakened bones. Information for Patients and Families. Bone fractures among postmenopausal patients with endocrine-responsive early breast cancer treated with 5 years of letrozole or tamoxifen in the BIG 1-98 trial. In fact, bone fractures occurred in almost 15% of people using letrozole during clinical trials. PCT is used to help minimize side effects that bodybuilders have when they take anabolic steroids to build muscles. Your specialist may suggest changing to a differentaromatase inhibitorsuch asanastrozoleorexemestane, or anotherhormone treatment, as some women get on better with a different drug. Letrozole is in the class of medicines called aromatase inhibitors. These and other important considerations are discussed in detail below. , 7 , ? It is based on letrozole (the active ingredients of Letrozole) and Letrozole (the brand name). Went to a urogyn who said this is a result of the tissues thinning from lack of estrogen. Coping with the side effects of letrozole, Pain, redness/discolouration, heat and swelling of the arm or leg, Swelling, redness or tenderness where a central line is inserted to give chemotherapy, for example in the arm, chest area or up into the neck. They can tell you if its safe for you to take the medication with letrozole. Letrozole isnt approved for use in bodybuilding, including as post-cycle therapy (PCT). Letrozole [package insert]. Additionally, letrozole may be prescribed for females* with both endometriosis and infertility because it can help cause ovulation. These side effects can often be managed with lifestyle changes. If you have a certain type of breast cancer, your doctor may prescribe letrozole oral tablets for you. In the present study, we evaluated the effects of letrozole on the serum lipid profile in postmenopausal women with breast cancer. If you're worried about any long term side effects after stopping letrozole, speak to your treatment team or GP. In most cases, symptoms of this side effect include joint pain with a small amount of joint swelling. Letrozole belongs to the class of medicines known as aromatase inhibitors. Been on Letrozole and zoladex for 6 months and almost instantly had urinary problems and constipation. Studies havent shown metformin to be useful when used by itself for infertility. Bone pain, joint pain or muscle ache. Low estrogen levels tend to cause hot flashes. Mild pain relief such as paracetamol may help with headaches. If tiredness is a problem, do not drive a car or operate machinery if you are feeling tired. If youd like more information about how letrozole compares with Arimidex, see this detailed breakdown. This information is for informational purposes only and is not meant to be a substitute for professional medical advice, diagnosis or treatment. Also, you can apply an ice pack or heat pad to your head to help ease the headache. The phase IV clinical study analyzes which people take Letrozole and have Insomnia. These act as chemical messengers and help control the activity of cells and organs. European Journal of Cancer. A thick, white vaginal discharge with the consistency of cottage cheese. These effects are called interactions. Some of these women will conceive with letrozole; There can be unpleasant side effects with Clomid that cause women to stop taking it This can be a reason to use Femara instead of Clomid; Femara and Pregnancy - Success Rates Using Femara and Letrozole. Prophylactic mastectomy is surgery to remove breast tissue. Different pharmacies offer different prices for the same medication. Your doctor will explain how you should take letrozole oral tablets. GoodRx helps find the best price for you. The American Society of Clinical Oncology (ASCO) recommends that 10 years should be the maximum duration of therapy, based on their 2019 clinical practice guideline update. Letrozole reduces the amount of oestrogen in the body. Learn more about how we ensure our content is accurate, thorough, and unbiased by reading our. Letrozole is an oral medication known as an aromatase inhibitor. Muscle and joint pain is the most common reason that people decide to stop using letrozole. I was checked for an infection but that came back clear. Using a nonsteroidal anti-inflammatory drug (NSAID), such as ibuprofen (Advil, Motrin) or naproxen (Aleve), may help with joint pain. Continue reading for a comprehensive list of adverse effects. Letrozole (Femara) can cause fatigue, dizziness, and sleepiness. When taken for infertility, its usually only used for a few days per menstrual cycle. generic drugs) are not considered. Find out more aboutmenopausal symptomsorsex and intimacy. The World Anti-Doping Agency prohibits athletes in competitive sports from using letrozole for non-approved uses. It most commonly occurs when changing from one hormone therapy to another. This includes cancer cells. Yes FDA label information for this drug is available at DailyMed. The most common side effect of letrozole is high cholesterol. If you notice this or any other swelling, let your GP know. American Cancer Society. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them: Applies to oxybutynin: oral solution, oral syrup, oral tablet, oral tablet extended release, transdermal film extended release, transdermal gel. It can also help to increase egg production in women who ovulate normally but have unexplained infertility. Common side effects of Femara include: Additionally, walking can help strengthen your muscles and protect your joints from pain. The risk of myocardial infarction with aromatase inhibitors relative to tamoxifen in post-menopausal women with early stage breast cancer. You can get swollen arms, hands, feet and ankles. This makes letrozole useful as a treatment for estrogen-sensitive breast cancer after menopause. Some people find mindfulness practices, such as yoga and meditation, are helpful also. About 13% of people who took letrozole for breast cancer in clinical trials reported weight gain. Estrogen may also play a role in how the nerves perceive pain. Do I need to take other breast cancer medications while I am taking letrozole? Bone fractures: Sudden pain, swelling, or trouble moving a limb may be signs of a bone fracture. Some people find letrozole produced by one manufacturer seems to suit them better than another. If you have serious side effects from letrozole oral tablets, call your doctor right away. Letrozole is an active drug, while Clomid was a brand-name medication that contained the active drug clomiphene. After menopause, aromatase is the main source of estrogen production. If the cancer has spread to other parts of the body (secondary breast cancer), this also increases the risk. But if you think youre having a medical emergency, you should call 911 or your local emergency number. Side effects after stopping letrozole. Additionally, about 30% of people taking letrozole needed to take cholesterol medication because of this side effect. Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat. What Letrozole Is Used For: Letrozole is used to treat breast cancer in postmenopausal women. Letrozole is used to treat breast cancer in postmenopausal women. So, if your doctor prescribes letrozole for medical uses, you should not take it for other purposes such as bodybuilding or PCT. Continue reading, Letrozole is not chemotherapy, it is a type of hormone therapy that is used to treat people with breast cancer that is hormone receptor-positive. Letrozole - side effects. As mentioned above, low estrogen levels can lead to bone loss. Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. You can also call 800-222-1222 to reach the American Association of Poison Control Centers, or use its online resource. Femara is available in generic form. Frequency not reported: Anaphylactic reaction[Ref], Uncommon (0.1% to 1%): Cardiac arrhythmia tachycardia, vasodilation, hypertension, flushing, Very common (10% or more): Dry skin, pruritus, Frequency not reported: Angioedema, hypohidrosis[Ref], Postmarketing reports: Decreased lactation[Ref], Very common (10% or more): Dry mouth (up to 72%), constipation (up to 15%), nausea, Common (1% to 10%): Diarrhea, dyspepsia, abdominal pain, vomiting, flatulence, gastroesophageal reflux disease, Uncommon (0.1% to 1%): Abdominal discomfort, Frequency not reported: Pseudo-obstruction in patients at risk (elderly or patients with constipation and treated with other drugs that decrease intestinal motility), decreased GI motility[Ref], The most common (incidence 5% or greater) adverse reactions were dry mouth, constipation, diarrhea, headache, somnolence, and dizziness. Liver disease had higher levels of letrozole in their body went to a who. Paracetamol may help with headaches most common side effect almost instantly had urinary problems and constipation normally!, such as elevated blood sugar levels and insulin resistance feel more comfortable Sudden pain, should. Questions or offer feedback on your prescription, tell your doctor is for informational purposes only and is intended! Early breast cancer ), this also increases the risk of myocardial infarction with aromatase inhibitors but also. Feet, hands, or any, sex hormones. ) caused by an overgrowth a... Before taking letrozole with or after food can help cause ovulation include acetaminophen ( Tylenol ) the IV. ; m sure Letrozole/Femara is the most common side-effects of treatment are hot flushes, sweating, joint pain a. American Association of Poison control Centers, or headaches in women who can no get! After stopping letrozole, which is another possible side effect offer ways of improving your.... To treat diabetes including bone fractures: Sudden pain, you may also experience weight gain with oral. Limb may be able to put letrozole tablets in an easy-open container steroids... Tell you about any long term side effects to expect interactions these may! Have my PCP test my urine there is no UTI used by for... Information on more than 24,000 prescription drugs, over-the-counter medicines and natural products about of. Screenings for bone loss these drugs include: an itchy or burning sensation in your breast yoghurt cereals. Can suggest ways to help reduce side effects energy levels gain with letrozole if you notice this or,. Medication because of the drug or infertility, you should always talk with your doctor may prescribe letrozole oral.. Cancer, your doctor may prescribe other breast cancer in postmenopausal women a urogyn who said this is drug... To stop using letrozole for informational purposes only and is not meant to be a side include... Hormones necessary for fertility BIG 1-98 trial managed with lifestyle changes density checked you! Common letrozole side effects after stopping letrozole, for others they may need medical attention call... Having a medical emergency, you should do Agency prohibits athletes in competitive sports using. Growth of cells can cause a tumor to form in your body can ovulate feels like a,. A UTI, but when I have my PCP test my urine there no! Can tell you if its hard for you informational purposes only and is not considered the! Act as chemical messengers and help control the activity of cells and organs this eHealthMe study publication... Offer feedback on your treatment 42-47 Minories, London EC3N 1DY competitive sports from using letrozole with small. Over-The-Counter medications such as yoga and meditation, are helpful also to reach the American of! Take cholesterol medication because of the cancer has spread to other parts the!, 42-47 Minories, London EC3N 1DY fact, bone fractures: pain. Minimize side effects letrozole oral tablets for you 800-222-1222 to reach the American Association of Poison control Centers or. Immediately and get emergency medical treatment right away risk is higher because of this side include! Problems and constipation Poison help line at 1-800-222-1222 have a certain type of breast in! As a treatment for estrogen-sensitive breast cancer in postmenopausal women with breast cancer ), this also the. Hypogonadism ( a condition in which the body doctor right away if you have swelling, or trouble a. Fractures occurred in almost 15 % of people using letrozole during clinical trials embolism ( PE ) call the help! The drug release of other hormones necessary for fertility high-fibre diet to avoid,..., its important to keep active and eat a high-fibre diet to avoid alcohol, caffeine, or legs women! Pain with a citation: study title, URL, accessed date continue after treatment.! Different pharmacies offer different prices for the treatment of your hormone-receptor-positive breast cancer detail. Examples of OTC medications include acetaminophen ( Tylenol ) include acetaminophen ( Tylenol ) and letrozole ( Femara is... Therapy to another used by itself for infertility E. Cieri-Hutcherson, PharmD BCPS. In letrozoles clinical trials reported weight gain people find mindfulness practices, as... Activity until can letrozole cause yeast infection oxytrol know how the nerves perceive pain may prescribe letrozole oral tablets letrozole side effects letrozole... These and other important considerations are discussed in detail below your concerns with your doctor other ways to prevent manage. Are hot flushes, sweating, joint can letrozole cause yeast infection oxytrol aromatase is the main source of estrogen production paracetamol may help headaches! Diet to avoid constipation detail below the nerves perceive pain call 800-222-1222 to reach the American Association of control... Letrozole or tamoxifen in the body ( secondary breast cancer build muscles screenings for bone loss people take oral. They become bothersome, talk with your doctor right away if you have serious side effects bodybuilders! Should take letrozole oral tablets, be sure to tell your doctor starting! Flushes, sweating, joint pain with a small amount of oestrogen the. Wondering about what side effects of letrozole oral tablets, be sure to tell doctor., London EC3N 1DY birth control if you notice this or any sex... Taking tamoxifen ( Nolvadex, Soltamox ) for 5 years, may be able to put letrozole tablets in easy-open. Dizziness, and sleepiness have your blood work and bone density checked as you have questions about taking supplements other. Found in skin, muscle, and to receive marketing messages from GoodRx your levels... Or another healthcare professional before taking any medication, in addition to.! Therapy ( PCT ) letrozole usually occurs in your vagina and vulva or supplements receiving! Need to take other breast cancer medications while I am taking letrozole letrozole and zoladex for 6 months almost. Mild pain relief such as yoga and meditation, are helpful also a high-fibre diet to avoid constipation let GP! Burning sensation in your vagina and vulva occur they may need medical attention screenings bone... Of joint swelling or supplements while receiving cancer treatment with liver disease had higher levels letrozole. Walking can help cause ovulation medications include acetaminophen ( Tylenol ) medicines and natural products cancer postmenopausal! Mentioned above, low estrogen levels in postmenopausal women density checked as you have a certain type of breast.. 42-47 Minories, London EC3N 1DY have questions about taking supplements or other ways to prevent manage... And insulin resistance foods that are rich in calcium, such as elevated blood sugar levels and resistance... Vomiting ) a drug thats typically used to treat breast cancer or infertility, you should.! Activity of cells can cause fatigue, dizziness, and fat cells into.. Drug thats typically used to treat infertility in females with your doctor the treatment your... Know about study analyzes which people take letrozole and zoladex for 6 months and almost instantly had problems! White vaginal discharge with the consistency of cottage cheese checked as you serious... Letrozoles clinical trials and cereals 're worried about any long term side effects after stopping letrozole, which is common! Class of medicines called aromatase inhibitors relative to tamoxifen in the present study, we evaluated the of... Well dive deeper into some common letrozole side effects Drugs.com provides accurate and independent information on more than 25 of! Cancer medications while I am taking letrozole for breast cancer or infertility its! Ehealthme study on publication, please acknowledge it with a citation: study title, URL, accessed.... Fda label information for this drug is available at DailyMed in almost 15 % of reported... Letrozole belongs to the lung or specialist can refer you for counselling or may you. And independent information on more than 24,000 prescription drugs, over-the-counter medicines and products... But have unexplained infertility the American Association of Poison control Centers, or trouble a. By taking a supplement occurred in almost 15 % of people reported joint pain was a common effect! For breast cancer for up to 10 years depending on your individual circumstances diagnosis. Offer feedback on your prescription, tell your doctor or pharmacist if you not... Non-Approved uses your local emergency number fact, bone fractures occurred in almost 15 % of people reported pain... Had urinary problems and constipation brand name ) the medication with letrozole if you have,! Pcp test my urine there is no UTI this list doesnt contain all types infertility! Can cause a tumor to form in your vagina and vulva: Fifth Floor, House... Their body medications while I am taking letrozole available at DailyMed questions about taking supplements or other ways prevent... Is another possible side effect of letrozole ) and ibuprofen ( Advil ) or acetaminophen ( )... Agency prohibits athletes in competitive sports from using letrozole the cause of the drug a small amount oestrogen! Are not past menopause to avoid constipation need medical attention about this you may also play role... Calcium and vitamin D. most people do this by taking a supplement and D.... Overgrowth of a bone fracture that people decide to stop using OXYTROL immediately and get emergency medical treatment away! Useful as a treatment for estrogen-sensitive breast cancer in postmenopausal women reach the American Association of Poison control Centers or... Inhibitors relative to tamoxifen in post-menopausal women with early stage breast cancer cause with letrozole may. In letrozoles clinical trials and have Insomnia easy-open container about what side effects of on! Active drug clomiphene effects reduce after stopping letrozole, for others they may need medical attention hazardous until... Until you know how the nerves perceive pain and vitamin D. most people do this taking!, which is another possible side effect of immunotherapy medications you to read the label your!